Author

Tangirala Ramakrishna

Centre for Cellular and Molecular BiologyORCID 0000-0002-0738-329XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:protein structure· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Bakthisaran Raman· 1 shared Ch. Mohan RaoiD· 1 shared Jayanthy JyothikumariD· 1 shared Mohammad Ahsan SaadiD· 1 shared Sushil ChandaniiD· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 4 mutual co-author links

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1 shared paperMolecular Biology

Bakthisaran Raman

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2 papers

Recent·Most cited

Molecular BiologyBiochimica et Biophysica Acta (BBA) - General SubjectsPeer-reviewedJan 13, 2021

Nucleosomal association and altered interactome underlie the mechanism of cataract caused by the R54C mutation of αA-crystallin

Mohammad Ahsan Saad, Bakthisaran Raman, Tangirala Ramakrishna, Ch. Mohan Rao

This study investigates how the R54C mutation in αA-crystallin causes cataract by altering its interactome and increasing nucleosomal association, rather than reducing chaperone activity.

6 citations

humanproteomics

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BioinformaticsbioRxivPreprintJun 13, 2018

Computational evidence of a new allosteric communication pathway between active sites and putative regulatory sites in the alanine racemase of Mycobacterium tuberculosis

Jayanthy Jyothikumar, Sushil Chandani, Tangirala Ramakrishna

The paper identifies new regulatory pockets in Mycobacterium tuberculosis alanine racemase and suggests they could be targets for specific TB drugs.

2 citations

humanprotein structure

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