NeuroscienceScience AdvancesPeer-reviewed
Targeting glial PD-1/PD-L1 restores microglial homeostasis and attenuates neuronal hyperactivity in Alzheimer's disease model
Taeyoung Park, Leechung Chang, Seung Won Chung…·Minah Suh
This study shows that targeting the PD-1/PD-L1 axis in glial cells improves microglial function and reduces neuronal hyperactivity in an Alzheimer's disease mouse model.
DOI 10.1126/sciadv.adx0731