Author

Larissa M. Bomfim

King's College LondonORCID 0000-0002-0753-8036Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Chi Wai Eric SoiD· 1 shared Cyril DoerdelmanniD· 1 shared Massimo LopesiD· 1 shared Tristan Gasparetto· 1 shared Tsz Kan FungiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperCancer Biology

Chi Wai Eric SoORCID

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1 paper

Recent·Most cited

Replication fork plasticity is a therapeutic vulnerability in acute myeloid leukemia

Cyril Doerdelmann, Tsz Kan Fung, Tristan Gasparetto, Larissa M. Bomfim, Chi Wai Eric So, Massimo Lopes

This study identifies replication fork plasticity as a key determinant of therapy response in AML, showing that PrimPol mediates resistance to PARPi and araC.

bioRxiv · Aug 18, 2026 · PreprintCancer Biology