Cancer BiologybioRxivPreprint
Replication fork plasticity is a therapeutic vulnerability in acute myeloid leukemia
Cyril Doerdelmann, Tsz Kan Fung, Tristan Gasparetto…·Massimo Lopes
This study identifies replication fork plasticity as a key determinant of therapy response in AML, showing that PrimPol mediates resistance to PARPi and araC.
DOI 10.64898/2026.08.13.744634