Developmental BiologyProceedings of the National Academy of SciencesPeer-reviewed
Linker histone regulates the myeloid versus lymphoid bifurcation of multipotent hematopoietic stem and progenitors
Kutay Karatepe, Bruna Mafra de Faria, Jian Zhang…·Shangqin Guo
This study shows that linker histone H1.0 regulates HSPC fate bias toward lymphoid or myeloid differentiation, with H1.0 levels decreasing in response to IFN signaling.
3 citations