Lipid scrambling via TMEM16F mediates the formation and release of apoptotic vesicles
Trieu Le, Yu Meng Li, Amra Sarić, Joost C. M. Holthuis, Sergio Grinstein, Spencer A. Freeman
This study shows that TMEM16F-mediated lipid scrambling drives the formation and release of apoptotic-like vesicles without affecting cytosolic calcium or the cytoskeleton.
bioRxiv · May 14, 2025 · PreprintCell Biology