Author

Michela Bruschi

University of UrbinoORCID 0000-0002-0804-7511Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Molecular Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:metabolomics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Alessandra FraternaleiD· 2 shared Francesca MonittolaiD· 2 shared Michele MenottaiD· 2 shared Rita CrinelliiD· 2 shared A. AntonelliiD· 1 shared Anastasia RicciiD· 1 shared C Bucci· 1 shared Carolina Zara· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMolecular Biology

Alessandra FraternaleORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Integrated metabolic and proteostatic profiling reveals remodeling of proteolytic pathways associated with redox-bioenergetic dysfunction in a PAHenu2 mouse model of phenylketonuria

Francesca Monittola, Elena Perla, Debora Libetti, A. Antonelli, Laura Graciotti, Davide Torre, Francesca Pierigè, Anastasia Ricci, Mauro Magnani, Marzia Bianchi, Sara Biagiotti, Luigia Rossi, Michele Menotta, Alessandra Fraternale, Rita Crinelli, Michela Bruschi

This study identifies proteolytic pathway remodeling and redox-bioenergetic dysfunction in a PKU mouse model through proteomics and metabolomics.

bioRxiv · Jul 9, 2026 · PreprintMolecular Biology

An N, S-acetylated L-cysteine-cysteamine conjugate hinders pyocyanin redox cycling to weaken Pseudomonas aeruginosa biofilm and dampens LPS-driven acute pulmonary inflammation

Michela Bruschi, Sofia Masini, Francesco Palma, Y Xiaoqiu, Cássia Lisboa Braga, Matteo Gregori, C Bucci, Francesca Bartoccini, Michele Menotta, Elisabetta Manuali, Lucia Minelli, Daniela Ligi, Ferdinando Mannello, Francesca Monittola, Carolina Zara, , Alessandra Fraternale

This paper identifies I-152 as a compound that disrupts Pseudomonas aeruginosa biofilm formation and reduces LPS-induced inflammation through redox cycling inhibition and anti-inflammatory effects.

bioRxiv · May 29, 2026 · PreprintPharmacology & Toxicology