Author

Gianluca Lattanzi

Istituto Nazionale di Fisica NucleareORCID 0000-0002-0808-6457Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Bioinformatics· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 2 Approach:deep learning· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Approach:simulation· 1

Frequent Co-Authors

Alessio BartocciiD· 2 shared Alessandro RomaneliD· 1 shared Carmen AbateiD· 1 shared Costanza Paternoster· 1 shared Davide DalfovoiD· 1 shared Domenico AlbergaiD· 1 shared Dritan SiliqiiD· 1 shared Fabio MazzaiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersPharmacology & Toxicology

Alessio BartocciORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Pharmacology & ToxicologyJournal of Chemical Information and ModelingPeer-reviewedJun 1, 2026

✦ In-depth digest

MD simulations of Human Sigma1 Receptor Trimer Uncovers Cholesterol Dependent Stabilization and Ligand Specific Dynamics

Vittoria Nanna, Costanza Paternoster, Alessio Bartocci…·Giuseppe Felice Mangiatordi

Across 12 µs of all-atom simulations, cholesterol stabilizes the sigma-1 receptor trimer, while haloperidol, unlike (+)-pentazocine, engages β6-strand W136 to tighten interprotomer coupling.

2 citations

humanprotein structure

𝕏 PostBluesky

BioinformaticsbioRxivPreprintNov 22, 2024

A common haplotype in the EXO5 gene can impact its protein structure and dynamics and modulate genome stability and cancer progression

Fabio Mazza, Davide Dalfovo, Alessio Bartocci…·Alessandro Romanel

This study investigates how common EXO5 haplotypes affect protein structure, dynamics, and cancer progression using genomic, clinical, and simulation data.

DOI 10.1101/2024.11.22.623165

humanDNA methylation

𝕏 PostBluesky