Cancer BiologyDevelopmental CellPeer-reviewed
Tuft cells transdifferentiate to neural-like progenitor cells in the progression of pancreatic cancer
Daniel James Salas-Escabillas, Megan T. Hoffman, Sydney M. Brender…·Howard C. Crawford
The paper shows that metaplastic tuft cells in pancreatic cancer transdifferentiate into neural-like progenitor cells, driven by Myc activity, and this transition is linked to poor patient survival.
21 citations