Author
Northwestern UniversityORCID 0000-0002-0832-4507Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
4 papers
Recent·Most cited
Eleanor A Degen, Shelby A. Blythe
The paper develops a reaction-diffusion framework to model Polycomb spreading during embryogenesis and shows PRC2 diffusion is enhanced by PRC1.
Natalie Gonzaga-Saavedra, Eleanor A Degen, Isabella V Soluri…·Shelby A. Blythe
The paper investigates how Polycomb modifications spread during Drosophila zygotic genome activation, showing nucleation-dependent propagation and the role of Zelda in licensing PREs.
Eleanor A Degen, Corinne Croslyn, Niall M. Mangan, Shelby A. Blythe
The paper shows that Bicoid-nucleosome competition sets a concentration threshold for hunchback transcription, constrained by genome replication in Drosophila embryos.
Eleanor A Degen, Natalie Gonzaga-Saavedra, Shelby A. Blythe
The paper develops a mathematical model to investigate how allostery and nucleation contribute to H3K27 methylation dynamics in early Drosophila embryogenesis.