Author

Marios Tomazou

The Cyprus Institute of Neurology & Genetics - Postgraduate EducationORCID 0000-0002-0836-5579Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1 Research Focus:variant effect prediction· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Anastasis OulasiD· 2 shared George M. SpyrouiD· 2 shared Maria ZantiiD· 2 shared Christina ChristodoulouiD· 1 shared George MinadakisiD· 1 shared Guy-Bart V. StaniD· 1 shared Jan RichteriD· 1 shared Karen Marie PolizziiD· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBioinformatics

Anastasis OulasORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

In depth analysis of Cyprus-specific mutations of SARS-CoV-2 strains using computational approaches

Anastasis Oulas, Jan Richter, Maria Zanti, Marios Tomazou, Kyriaki Michailidou, Kyproula Christodoulou, Christina Christodoulou, George M. Spyrou

This study identifies a Cyprus-specific SARS-CoV-2 mutation (S6059F) and assesses its potential association with increased viral virulence using computational methods.

BMC Genomic Data · Nov 13, 2021Peer-reviewedBioinformatics

Generalized linear models provide a measure of virulence for specific mutations in SARS-CoV-2 strains

Anastasis Oulas, Maria Zanti, Marios Tomazou, Margarita Zachariou, George Minadakis, Marilena M. Bourdakou, Pavlos Pavlidis, George M. Spyrou

This paper uses generalized linear models to identify SARS-CoV-2 mutations associated with changes in viral virulence, highlighting two mutations with opposing effects on deaths and cases per million.

PLoS ONE · Jan 26, 2021Peer-reviewedBioinformatics

Computational Re-Design of Synthetic Genetic Oscillators for Independent Amplitude and Frequency Modulation

Marios Tomazou, Mauricio Barahona, Karen Marie Polizzi, Guy-Bart V. Stan

This work computationally redesigns synthetic genetic oscillators to enable independent amplitude and frequency modulation using tuneable degradation and additional input signals.

Cell Systems · Apr 1, 2018Peer-reviewedSynthetic Biology