Author

Valéria C. Rolla

Instituto Nacional de Infectologia Evandro ChagasORCID 0000-0002-0841-1408Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:GWAS / association mapping· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Afrânio Lineu KritskiiD· 1 shared Alberto L. García‐BasteiroiD· 1 shared Alemnew F. DagnewiD· 1 shared Alexander C. SchmidtiD· 1 shared Alice M S Andrade· 1 shared Amelia HouanaiD· 1 shared Amy Çinar· 1 shared Anne WajjaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Afrânio Lineu KritskiORCID

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Author profile →

2 papers

Recent·Most cited

Associations Between QuantiFERON-TB Gold Plus IFNγ Concentrations and Progression to Symptomatic Tuberculosis in Global High-Burden TB Settings

Justine E. Sunshine, Michael Shaffer, Linda L. Han, Deepali Gaikwad, Amelia Houana, Maria Tarcela Gler, Sri Rezeki Hadinegoro, Willem Albert Hanekom, Javier R. Lama, Monde Muyoyeta, Sissy Musala, Videlis Nduba, Valéria C. Rolla, Tapash Roy, Jayne S. Sutherland, , Alberto L. García‐Basteiro

This study finds higher QuantiFERON-TB Gold Plus IFNγ concentrations are associated with progression to symptomatic TB and meet WHO biomarker thresholds.

Open Forum Infectious Diseases · Jul 1, 2026Peer-reviewedImmunology

Genome-wide association study in Brazil identifies genetic susceptibility to tuberculosis with single-cell gene effects

Kimberly A. Dill‐McFarland, Bruno B. Andrade, Marina Cruvinel Figueiredo, Alice M S Andrade, Francys Avendaño-Rangel, Marcelo Cordeiro‐Santos, Afrânio Lineu Kritski, Valéria C. Rolla, Juan Manuel Cubillos-Angulo, Spyros A. Kalams, Josh D Simmons, Jared M. Oakes, Jonathan Avila, Helder Imoto Nakaya, Rama Gangula, , Thomas R. Hawn

This study identifies genetic risk factors for tuberculosis in Brazil using GWAS and single-cell transcriptomics, finding SNPs associated with gene expression in multiple cell types.

medRxiv · Mar 13, 2025 · PreprintGenetic & Genomic Medicine