Author

Afrânio Lineu Kritski

Universidade Federal do Rio de JaneiroORCID 0000-0002-5900-6007Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Research Focus:GWAS / association mapping· 1 Organism:human· 1

Frequent Co-Authors

Alice M S Andrade· 1 shared Anna Cristina Calçada CarvalhoiD· 1 shared Bruno B. AndradeiD· 1 shared Chuan-Chin HuangiD· 1 shared Francys Avendaño-RangeliD· 1 shared Gustavo AmorimiD· 1 shared Helder Imoto NakayaiD· 1 shared Jared M. OakesiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Alice M S Andrade

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2 papers

Recent·Most cited

Genome-wide association study in Brazil identifies genetic susceptibility to tuberculosis with single-cell gene effects

Kimberly A. Dill‐McFarland, Bruno B. Andrade, Marina Cruvinel Figueiredo, Alice M S Andrade, Francys Avendaño-Rangel, Marcelo Cordeiro‐Santos, Afrânio Lineu Kritski, Valéria C. Rolla, Juan Manuel Cubillos-Angulo, Spyros A. Kalams, Josh D Simmons, Jared M. Oakes, Jonathan Avila, Helder Imoto Nakaya, Rama Gangula, , Thomas R. Hawn

This study identifies genetic risk factors for tuberculosis in Brazil using GWAS and single-cell transcriptomics, finding SNPs associated with gene expression in multiple cell types.

medRxiv · Mar 13, 2025 · PreprintGenetic & Genomic Medicine

Dysglycemia is associated with Mycobacterium tuberculosis lineages in tuberculosis patients of North Lima - Peru.

Kattya Lopez, María B. Arriaga, Juan Aliaga, Nadia N. Barreda, Oswaldo M. Sanabria, Chuan-Chin Huang, Zibiao Zhang, Ruth García-de-la-Guarda, Leonid W. Lecca, Anna Cristina Calçada Carvalho, Afrânio Lineu Kritski, Roger I. Calderon

The paper investigates the association between dysglycemia and Mycobacterium tuberculosis lineages in TB patients, finding specific lineages linked to diabetes and pre-diabetes comorbidities.

PLoS ONE · Jan 28, 2021Peer-reviewedMolecular Biology