Author

Andrew C. Giles

Ambry Genetics (United States)ORCID 0000-0002-0875-0696Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:benchmark study· 1 Research Focus:benchmarking· 1 Organism:C. elegans· 1 Research Focus:database / resource· 1 Approach:experimental assay· 1

Frequent Co-Authors

Aastha Gandhi· 1 shared ALEXANDER R. GOTTSCHALKiD· 1 shared Alice E. DavidsoniD· 1 shared Ana Lisa Taylor TavaresiD· 1 shared Anna B Verwillow· 1 shared Anne GregoriD· 1 shared Annemieke M Aartsma-RusiD· 1 shared Aubrie SoucyiD· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Aastha Gandhi

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2 papers

Recent·Most cited

Consensus guidelines for eligibility assessment of pathogenic variants to antisense oligonucleotide treatments

David Cheerie, Margaret M. Meserve, Danique Beijer, Charu Kaiwar, Logan Newton, Ana Lisa Taylor Tavares, Aubrie Soucy, Emma Sherrill, Stefanie Leonard, Stephan Sanders, Emily J. Blake, Nour M. Elkhateeb, Aastha Gandhi, Nicole Si Yan Liang, J. Morgan, , Marlen C. Lauffer

The paper presents consensus guidelines for assessing pathogenic variants' eligibility for antisense oligonucleotide treatments, including classification criteria and considerations for different therapeutic approaches.

The American Journal of Human Genetics · Mar 26, 2025Peer-reviewedGenetic & Genomic Medicine

Circuit Degeneracy Facilitates Robustness and Flexibility of Navigation Behavior in C. elegans

Muneki Ikeda, Shunji Nakano, Andrew C. Giles, Wagner Steuer Costa, ALEXANDER R. GOTTSCHALK, Ikue Mori

The paper shows that overlapping neural circuits in C. elegans enable robust and flexible thermotaxis behavior through compensatory mechanisms and context-dependent regulation.

bioRxiv · Aug 5, 2018 · PreprintNeuroscience