Hyun Goo Woo

This study shows that loss of Cotl1 in mice reduces platelet-mediated osteoclastogenesis, leading to osteopetrosis, and identifies a genetic association between COTL1 variants and bone density in humans.

This study investigates Omicron's enhanced ACE2 binding and antibody escape by analyzing mutations in the spike protein and their impact on binding free energies and electrostatic potentials.

The paper designs and tests peptide biologics that neutralize SARS-CoV-2 S1 and block S1-ACE2 interaction in vitro, showing varying effectiveness among different peptides.

The paper introduces a functional genomic complexity (FGC) score to assess genomic heterogeneity in liver cancer, finding higher FGC correlates with worse prognosis and immune evasion.