ImmunologybioRxivPreprint
Toll-like receptor 9 contributes in microglial activation and lysosomal dysfunction to promote Alzheimer disease
Moïse de Lavergne, Lucie Mazzola, Katrina Podsypanina…·Bénédicte Manoury
This study identifies TLR9's role in microglial activation and lysosomal dysfunction in Alzheimer's disease, showing its inhibition reduces pathology and cognitive defects.