Clemens Ruppert

This study evaluates the anti-fibrotic effects of LTI-03 in IPF patient-derived precision cut lung slices, showing dose-dependent reduction of fibrotic markers.

This study evaluates the antifibrotic effects of OTR4120 in lung fibrosis models, showing reduced collagen deposition and fibroblast activation.

This study identifies an autocrine role for Hedgehog signaling in regulating epithelial cell proliferation and differentiation in the trachea.

This study identifies Myh10 as critical for alveolar development and ECM remodeling, linking its deficiency to pulmonary disease and emphysema.