Author

Yago Amigo Pinho Jannini de Sá

Cedars-Sinai Medical CenterORCID 0000-0003-4137-1257Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1 Assay:proteomics· 1

Frequent Co-Authors

Ana Lúcia CoelhoiD· 2 shared BreAnne MacKenzieiD· 2 shared Brecht CreynsiD· 2 shared Brian Windsor· 2 shared Cory M. HogaboamiD· 2 shared Andreas GüntheriD· 1 shared Clemens AigneriD· 1 shared Clemens RuppertiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersPharmacology & Toxicology

Ana Lúcia CoelhoORCID

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2 papers

Recent·Most cited

Pharmacology & ToxicologyiSciencePeer-reviewedAug 26, 2025

Pre-clinical proof-of-concept of anti-fibrotic activity of caveolin-1 scaffolding domain peptide LTI-03 in ex vivo precision cut lung slices from patients with Idiopathic Pulmonary Fibrosis

BreAnne MacKenzie, Poornima Mahavadi, Yago Amigo Pinho Jannini de Sá…·Andreas Günther

This study evaluates the anti-fibrotic effects of LTI-03 in IPF patient-derived precision cut lung slices, showing dose-dependent reduction of fibrotic markers.

4 citations

humanbulk RNA-seq

𝕏 PostBluesky

ImmunologyBiomedicinesPeer-reviewedMar 26, 2025

Caveolin scaffolding domain (CSD) peptide LTI-2355 modulates the phagocytic and synthetic activity of lung derived myeloid cells in Idiopathic Pulmonary Fibrosis (IPF) and Post-acute sequelae of COVID-fibrosis (PASC-F)

Brecht Creyns, BreAnne MacKenzie, Yago Amigo Pinho Jannini de Sá…·Cory M. Hogaboam

This study shows that the CSD peptide LTI-2355 improves phagocytic and reduces pro-inflammatory activity in myeloid cells from IPF and PASC-F patients.

7 citations

humanflow cytometry

𝕏 PostBluesky