Arlin Stoltzfus

The paper quantifies how taxon-specific mutational biases influence adaptive amino acid substitutions across 14 species.

gpmap-tools uses Gaussian processes to infer and visualize genotype-phenotype maps with higher-order epistasis; across 262,144 Shine-Dalgarno variants it reveals register-specific peaks linked by three-nucleotide-offset ridges.

The paper analyzes over 350,000 amino acid replacements to show that fitness effects follow a maximum entropy distribution, with implications for mutational prediction and protein design.

Phylotastic provides an accessible system for on-the-fly delivery of phylogenetic trees, enabling users to retrieve species phylogenies with minimal effort.

The paper tests whether conservative transitions are more favorable in protein evolution by analyzing mutation fitness effects, finding weak support for this hypothesis.

This paper introduces two new Bayesian prior methods for calibrating phylogenetic trees using fossil data and shows they improve divergence time accuracy.