Author

Leonid A. Sazanov

Institute of Science and Technology AustriaORCID 0000-0002-0977-7989Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 2 Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Organism:E. coli· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Ziyu ZhaoiD· 2 shared Irene VercellinoiD· 1 shared Julian P. WhiteleggeiD· 1 shared Karim MaghlaouiiD· 1 shared Peter Julian NixoniD· 1 shared Wojciech BiałekiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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2 shared papersBiochemistry

Ziyu ZhaoORCID

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2 papers

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedJul 8, 2026

Cryo-EM structures of naturally occurring dimeric photosystem II complexes lacking the Mn4CaO5 cluster

Ziyu Zhao, Irene Vercellino, Julian P. Whitelegge…·Leonid A. Sazanov

The paper determines cryo-EM structures of dimeric PSII intermediates from cyanobacteria, revealing mechanisms of Mn4CaO5 cluster assembly/disassembly and photoinactivation.

1 citation

bacteria (other)cryo-EM

BiochemistryMolecular CellPeer-reviewedJun 22, 2026

Structure of E. coli Twin-arginine translocase (Tat) complex with bound cargo

Ziyu Zhao, Leonid A. Sazanov

The paper presents the atomic cryo-EM structure of an E. coli TatB3C3 complex bound to SufI, revealing a novel architecture and dual-contact mechanism for substrate engagement.

1 citation

E. colicryo-EM