Author

Sean C. McConnell

University of ChicagoORCID 0000-0002-0988-5373Unclaimed ORCID profile · follow to get notified of new preprints

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Sean C. McConnell1 paper

Biology Disciplines

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Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Organism:zebrafish· 2 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Jill L. O. de JongiD· 2 shared Abigail Leonard· 1 shared Arkadi ShwartziD· 1 shared Caitlin K. GribbiniD· 1 shared Carolyn R. Maskin· 1 shared Clara Kao· 1 shared Courtney A. Balgobin· 1 shared Darya Mailhiot· 1 shared

Activity by Year

2020-2022 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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2 shared papersGenomics

Jill L. O. de JongORCID

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2 papers

Recent·Most cited

GenomicsbioRxivPreprintJun 8, 2022

Immune gene variation associated with chromosome-scale differences among individual zebrafish genomes

Sean C. McConnell, Kyle M. Hernandez, Jorge Andrade, Jill L. O. de Jong

The paper examines immune gene variation across three zebrafish genomes, revealing high sequence divergence and structural variation, particularly in the MHC and NLR gene clusters on chromosome 4.

1 citation

zebrafishwhole-genome sequencing

𝕏 PostBluesky

Molecular BiologyNucleic Acids ResearchPeer-reviewedFeb 5, 2020

A total synthetic approach to CRISPR/Cas9 genome editing and homology directed repair

Sara E. DiNapoli, Raúl Martinez-McFaline, Caitlin K. Gribbin…·Yariv J. Houvras

The paper demonstrates the effectiveness of synthetic sgRNAs and dsDNA templates for efficient HDR and genome editing in zebrafish.

45 citations

zebrafishCRISPR screen

𝕏 PostBluesky