Author

Claudia Fournier

GSI Helmholtz Centre for Heavy Ion ResearchORCID 0000-0002-1007-9934Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Alexander HelmiD· 2 shared Marco DuranteiD· 2 shared Anggraeini Puspitasari-KokkoiD· 1 shared Anna RehmiD· 1 shared Burkhard JakobiD· 1 shared Christoph SchuyiD· 1 shared Cristina Totis· 1 shared Daria BoscoloiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiophysics

Alexander HelmORCID

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2 papers

Recent·Most cited

Induction of cytoplasmic dsDNA and cGAS-STING immune signaling after exposure of breast cancer cells to X-rays or high energetic carbon ions

Cristina Totis, Nicole Averbeck, Burkhard Jakob, Maik Schork, Gaia Volpi, Dennis F Hintze, Marco Durante, Claudia Fournier, Alexander Helm

This study shows carbon ions induce more cytosolic dsDNA and interferon-β in breast cancer cells than X-rays, enhancing innate immune signaling.

Advances in Radiation Oncology · Apr 8, 2025Peer-reviewedBiophysics

FLASH Bragg-peak irradiation with a therapeutic carbon ion beam: first in vivo results

Walter Tinganelli, Anggraeini Puspitasari-Kokko, Olga Sokol, Alexander Helm, Palma Simoniello, Christoph Schuy, Sylvie Lerchl, Denise Eckert, Julius Oppermann, Anna Rehm, Stefan Janssen, Denise Engel, Ralf Moeller, Rossana Romano, Felix Horst, , Uli Andreas Weber

This study shows that FLASH irradiation with carbon ions spares normal tissue and maintains tumor control in mice, similar to conventional dose-rate treatments.

International Journal of Radiation Oncology*Biology*Physics · Nov 26, 2024Peer-reviewedCancer Biology