Dynamic optimization reveals alveolar epithelial cells as key mediators of host defense in invasive aspergillosis
Jan Ewald, Flora Rivieccio, Lukáš Radosa, Stefan Schuster, Axel A. Brakhage, Christoph Kaleta
This study uses dynamic optimization to analyze host-pathogen interactions in invasive aspergillosis, identifying key roles for epithelial cells and neutrophils in immune response and fungal virulence.
PLoS Computational Biology · Dec 13, 2021Peer-reviewedSystems Biology