Author

Yuki Kimura

Waseda UniversityORCID 0000-0002-1011-3485Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein design· 2 Assay:protein structure· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Organism:E. coli· 1 Assay:protein sequence· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Daisuke UmenoiD· 2 shared Miyu Tsukada· 1 shared Shigeko Kawai‐NomaiD· 1 shared Yuki Yanai· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 4 mutual co-author links

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2 shared papersSynthetic Biology

Daisuke UmenoORCID

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2 papers

Recent·Most cited

Fabrication, evolution, and mutual conversion of D-fucose-activatable and -repressible acetyltransferase upon mutations

Yuki Yanai, Miyu Tsukada, Yuki Kimura, Daisuke Umeno

The paper demonstrates how mutations can convert between D-fucose-activatable and -repressible acetyltransferase switches in fusion proteins.

ACS Synthetic Biology · Apr 30, 2025Peer-reviewedSynthetic Biology

Mutational destabilisation accelerates the evolution of novel sensory and network functions

Yuki Kimura, Shigeko Kawai‐Noma, Daisuke Umeno

The paper shows that mutational destabilisation enables rapid evolution of novel sensory functions in AraC proteins through a BIF mechanism, outperforming traditional allosteric modes.

bioRxiv · Nov 23, 2023 · PreprintSynthetic Biology