Birth, cell fate and behavior of progenitors at the origin of the cardiac mitral valve
Batoul Farhat, Ignacio Bordeu, Bernd Jagla, Hugo Blanc, Karine Loulier, Benjamin D. Simons, Emmanuel Beaurepaire, Jean Livet, Michel Pucéat
The paper identifies the origin, fate, and clonal contribution of endocardial progenitors to the development of the cardiac mitral valve using single-cell RNA sequencing and genetic tracing in mice.
bioRxiv · Aug 6, 2022 · PreprintDevelopmental Biology