Bernd Jagla

CyFj11: FlowJo v11 Workspace Import and Legacy Format Export for R-Based Flow Cytometry Analysis

CyFj11 enables importing FlowJo v11 workspaces into R and exporting R-based gates back to FlowJo, ensuring interoperability between gating tools and statistical analysis environments.

NK cells undergo transcriptional and functional reprogramming following Streptococcus pneumoniae infection

This study uses single-cell RNA-seq to show that NK cells reprogram transcriptionally and functionally after Streptococcus pneumoniae infection, revealing new roles in bacterial immunity.

Birth, cell fate and behavior of progenitors at the origin of the cardiac mitral valve

The paper identifies the origin, fate, and clonal contribution of endocardial progenitors to the development of the cardiac mitral valve using single-cell RNA sequencing and genetic tracing in mice.

Macrophage-mediated epimorphosis in pig heart with right ventricular failure

The paper shows that cardiac macrophages in pigs with right ventricular failure drive cardiomyocyte de-differentiation and regeneration through epimorphosis.

SCHNAPPs - Single Cell sHiNy APPlication(s)

SCHNAPPs is a Shiny-based tool for bench-scientists to analyze scRNA-seq data, offering quality control, clustering, differential expression, and visualization with reproducible reporting.