Tomislav Domazet‐Lošo

Evolutionary expression patterns in developing biofilms of uropathogenic Escherichia coli reveal embryo-like features

This study shows that uropathogenic E. coli biofilms exhibit evolutionary stratification, with gene expression becoming younger and more divergent as biofilms develop.

Massive outsourcing of energetically costly amino acids at the origin of animals

The paper shows that essential amino acids are more costly to synthesize than non-essential ones, leading to their outsourcing in animals due to selective pressures under high respiratory conditions.

Contrasting macroevolutionary patterns in the human N-glycosylation pathway

This study examines the evolutionary origins of glycosylation machinery genes and their targets in humans, revealing ancient and recent evolutionary patterns in the N-glycosylation pathway.

Evolutionary trends in the emergence of skeletal cell types.

This study investigates the evolutionary trends in skeletal cell type emergence, finding that lineage-specific genes drove the diversification of osteoblasts and hypertrophic chondrocytes from an ancestral chondrocyte-like state.

Convergence in amino acid outsourcing between animals and predatory bacteria

The paper compares amino acid outsourcing in animals and predatory bacteria, finding convergence in energy-driven selection for AA auxotrophies in Bdellovibrionota but not in Myxococcota.

Bacterial amino acid auxotrophies enable energetically costlier proteomes

This study shows that bacterial amino acid auxotrophies are shaped by energy management and correlate with the cost of their proteomes, similar to animals.

Somatic embryogenesis of grapevine (Vitis vinifera) expresses a transcriptomic hourglass

The paper investigates whether the hourglass-shaped ontogeny-phylogeny correlation observed in Arabidopsis zygotic embryogenesis is preserved in grapevine somatic embryogenesis, finding that the heart stage has the most conserved transcriptome.