Moisés Selman

Lung progenitors exhaustion in response to microenvironment stress during aging

This study investigates how aging and Zmpste24 deficiency affect lung progenitor cells and their fibroblast niche, showing increased susceptibility to stress and impaired regeneration.

Autophagy impairment by ATG4B deficiency reduces experimental hypersensitivity pneumonitis severity

This study shows that autophagy impairment in Atg4b-deficient mice reduces hypersensitivity pneumonitis severity by limiting inflammation and immune responses.

Peripheral Blood Single-Cell Sequencing Uncovers Common and Specific Immune Aberrations in Fibrotic Lung Diseases

This study uses single-cell RNA sequencing to identify common and distinct immune aberrations in IPF and FHP, revealing shared monocyte features and disease-specific lymphocyte and receptor repertoires.

PulmonDB: a curated lung disease gene expression database

PulmonDB provides a curated database and R library for exploring gene expression in COPD and IPF, enabling differential expression analysis and hypothesis generation.