Jiami Guo

The paper introduces scSCOPE, a method for identifying reproducible and functionally relevant marker genes from scRNA-seq data, showing improved consistency across datasets.

This study shows primary cilia modulate astrocyte diversity and function through Shh signaling and intracellular balance, affecting neuronal development and behavior.

This study creates a single-cell transcriptomic catalog of mouse cortical development, revealing cell types, states, and their relationships, and linking gene expression to disease subtypes.