The distinct roles of calcium in rapid control of neuronal glycolysis and the tricarboxylic acid cycle
Carlos Manlio Díaz‐García, Dylan J. Meyer, Nidhi Nathwani, Mahia Rahman, Juan Ramón Martínez‐François, Gary Yellen
The paper investigates the role of calcium in neuronal energy metabolism, finding that mitochondrial Ca2+ uptake drives NADH buildup in the TCA cycle, while cytosolic glycolytic NADH increases are driven by energy demand, not Ca2+ signaling.
eLife · Feb 8, 2021Peer-reviewedNeuroscience