Carlos Manlio Díaz‐García

COGNITIVE HETEROGENEITY AND AGING: AN AGE-INDEPENDENT CILIARY GENE PROGRAM TRACKS COGNITIVE RESILIENCE IN MICE

This study identifies a ciliary gene program linked to cognitive resilience in mice, independent of age, by integrating behavioral data with transcriptomic profiling.

Metabolic regulation of species-specific developmental rates

The paper shows that metabolic rates influence developmental speed in mouse and human embryos, with mouse cells having higher metabolic rates and faster segmentation clock periods.

The Na+/K+ pump dominates control of glycolysis in hippocampal dentate granule cells

The paper shows that the Na+/K+ pump, not Ca2+ influx, primarily drives glycolysis activation in hippocampal dentate granule cells following neuronal stimulation.

The distinct roles of calcium in rapid control of neuronal glycolysis and the tricarboxylic acid cycle

The paper investigates the role of calcium in neuronal energy metabolism, finding that mitochondrial Ca2+ uptake drives NADH buildup in the TCA cycle, while cytosolic glycolytic NADH increases are driven by energy demand, not Ca2+ signaling.