Author

Sarah A. Connolly

DePaul UniversityORCID 0000-0002-1038-3952Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2

Frequent Co-Authors

Qing FaniD· 2 shared Richard LongneckeriD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

2 top collaborators · 1 mutual co-author link

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2 shared papersMicrobiology

Qing FanORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintJan 26, 2026

Glycoprotein C Mutations Regulate the Plaque Size of Fusion-Defective Herpes Simplex Virus

Qing Fan, Richard Longnecker, Sarah A. Connolly

This study shows that mutations in glycoprotein C (gC) can partially restore plaque size and fusion function in HSV-1 fusion-defective viruses, indicating gC acts as a conditional accessory regulator.

DOI 10.64898/2026.01.26.701780

humanexperimental assay

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MicrobiologymBioPeer-reviewedDec 5, 2025

Species-Specific gB Ectodomain Interactions and Cytoplasmic Domain Stability Regulate Herpes Simplex Virus Fusion

Qing Fan, Richard Longnecker, Sarah A. Connolly

This study identifies regions of gB responsible for species-specific interactions and shows how its domains balance fusion promotion and restraint.

3 citations

humanexperimental assay

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