Author

Jennifer Y. Cui

Brown UniversityORCID 0000-0002-1054-0786Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Assay:protein structure· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Brenda M. RubensteiniD· 2 shared George P. LisiiD· 2 shared Anna S Bock· 1 shared David C. DalgarnoiD· 1 shared Fuming ZhangiD· 1 shared Gabriel Monteiro da SilvaiD· 1 shared Iz Varghese· 1 shared Mariana Floody· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 20 mutual co-author links

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2 shared papersBiophysics

Brenda M. RubensteinORCID

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2 papers

Recent·Most cited

Exploring the GM-CSF Histidine Triad as a Modulator of Structure, Molecular Motion, and Ligand Binding

Jennifer Y. Cui, Iz Varghese, Anna S Bock, Mariana Floody, Fuming Zhang, Brenda M. Rubenstein, George P. Lisi

This study investigates how histidine residues in GM-CSF affect its structure, flexibility, and ligand binding at physiological pH.

RSC Chemical Biology · Jan 1, 2026Peer-reviewedBiophysics

Predicting Relative Populations of ProteinConformations without a Physics Engine UsingAlphaFold2

Gabriel Monteiro da Silva, Jennifer Y. Cui, David C. Dalgarno, George P. Lisi, Brenda M. Rubenstein

This paper uses AlphaFold2 to predict protein conformational populations and mutation effects without a physics engine, achieving over 80% accuracy on two proteins.

bioRxiv · Jul 25, 2023 · PreprintBioinformatics