Author

Sirui Wu

China Mobile (China)ORCID 0000-0002-1057-6121Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:graph neural network· 1 Organism:human· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Adi ZhengiD· 1 shared Anhui Du· 1 shared Deyu MengiD· 1 shared Fanding XuiD· 1 shared Fangjun Chen· 1 shared Hao LiiD· 1 shared Jiajia Xiao· 1 shared Jiangang LongiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperSystems Biology

Adi ZhengORCID

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2 papers

Recent·Most cited

Systems BiologyCellular and Molecular Gastroenterology and HepatologyPeer-reviewedOct 1, 2026

Integrative multi-omics and multi-trait analysis prioritizes regulatory mechanisms and genes for metabolic dysfunction-associated steatotic liver disease

Zhaode Feng, Fangjun Chen, Jiajia Xiao…·Hao Li

This study identifies 39 candidate genes involved in MASLD progression using multi-omics and multi-trait analysis, validated through experimental models and an interactive web portal.

DOI 10.1016/j.jcmgh.2026.101928

humanbulk RNA-seq

𝕏 PostBluesky

BioinformaticsActa Physico-Chimica SinicaPeer-reviewedNov 4, 2025

MolUNet++: Adaptive-grained Explicit Substructure and Interaction Aware Molecular Representation Learning

Fanding Xu, Zhiwei Yang, Sirui Wu…·Jiangang Long

MolUNet++ improves molecular representation learning by explicitly analyzing substructures and interactions, outperforming traditional GNN models in prediction tasks and offering interpretable insights.

1 citation

graph neural networkdrug response / drug discovery

𝕏 PostBluesky