Protein Function Prediction via Contig-Aware Multi-Level Feature Integration
Liangwei Yang, Kaixin Du, Yintong Lu, Mengzhu Wang, Hongxing Zhang, Shuo Yang, Yu‐Hsuan Lin, Jiaming Zhuo, Duoyue Zhang, Yiqi Jiang, Xianglilan Zhang, Shuai Cheng Li
This paper introduces CAML, a deep learning model that improves protein function prediction by integrating sequence, structure, and contig-level CDS topology features, achieving significant performance gains over existing methods.
bioRxiv · Aug 7, 2025 · PreprintBioinformatics