Duoyuan Chen

This study reconstructs the evolutionary assembly of a conserved cortical axis across vertebrates using spatial transcriptomics and single-nucleus RNA-seq, revealing conserved molecular programs and convergent evolution in brain circuitry.

OneGenome-Rice (OGR) is a genomic foundation model for rice pre-trained on 422 genomes, outperforming existing models in 11 tasks and enabling downstream applications like trait analysis and gene expression prediction.

This study presents a single-cell and spatial transcriptomic atlas of the budgerigar brain, revealing structural and developmental insights into avian neurogenesis and brain evolution.

The paper creates a single-cell atlas of amniote brains to study cell type diversification and identifies species-specific gene expression patterns and novel cell subtypes.

This study uses deep genome skimming data to analyze whole-genome duplication events in polyploid Prunus species, revealing allopolyploidization as a dominant evolutionary mechanism.