Author

Adrien Le Meur

Centre National de la Recherche ScientifiqueORCID 0000-0002-1073-9867Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Evolutionary Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:variant calling· 3 Assay:whole-genome sequencing· 3 Organism:bacteria (other)· 1 Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Guislaine RefrégieriD· 2 shared Rima Zein-EddineiD· 2 shared Anders GötherströmiD· 1 shared Antonio Blanchet· 1 shared Eduardo Arrieta-DonatoiD· 1 shared Emrah KırdökiD· 1 shared Federico Sánchez‐QuintoiD· 1 shared Gülşah Merve KılınçiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersBioinformatics

Guislaine RefrégierORCID

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3 papers

Recent·Most cited

GenomicsCommunications BiologyPeer-reviewedJul 13, 2026

Ancestry, admixture, and pathogens in contemporaneous Neolithic farmers and foragers on the Island of Gotland

Magdalena Fraser, Federico Sánchez‐Quinto, Emrah Kırdök…·Mattias Jakobsson

The paper analyzes ancestry, admixture, and pathogens in Neolithic farmers and foragers from Gotland, finding recent gene flow and widespread Yersinia pestis strains.

1 citation

humanwhole-genome sequencing

BioinformaticsbioRxivPreprintOct 4, 2025

Improving the benchmark of variant calling in clonal bacteria using more realistic in silico genomes, the case of Mycobacterium tuberculosis

Adrien Le Meur, Ricardo C. Rodŕıguez de la Vega, Rima Zein-Eddine, Guislaine Refrégier

The paper benchmarks variant calling in Mycobacterium tuberculosis using realistic in silico genomes, showing that current methods miss variants and are biased.

DOI 10.1101/2025.10.04.680280

bacteria (other)whole-genome sequencing

Evolutionary Biologynpj Antimicrobials and ResistancePeer-reviewedApr 29, 2025

Genome wide analyses reveal the role of mutator phenotypes in the emergence of drug resistance in Mycobacterium tuberculosis

Rima Zein-Eddine, Adrien Le Meur, Stéphane Skouloubris…·Hannu Myllykallio

The paper identifies 18 novel SNPs in DNA repair genes linked to drug resistance in Mtb using genome-wide analysis of 53,589 whole-genomes.

16 citationstop 1%

whole-genome sequencingstatistical model