BioinformaticsbioRxivPreprint
Improving the benchmark of variant calling in clonal bacteria using more realistic in silico genomes, the case of Mycobacterium tuberculosis
Adrien Le Meur, Ricardo C. Rodŕıguez de la Vega, Rima Zein-Eddine, Guislaine Refrégier
The paper benchmarks variant calling in Mycobacterium tuberculosis using realistic in silico genomes, showing that current methods miss variants and are biased.
DOI 10.1101/2025.10.04.680280