Causal SNP regulating FAM13B expression identified for the Chr. 5q31 atrial fibrillation susceptibility loc
Gregory Tchou, Daniela Ponce‐Balbuena, Nana Liu, Shamone R. Gore-Panter, Jeffrey Hsu, Fang Liu, Emmanuel Opoku, Gregory Brubaker, Sarah M. Schumacher, Christine Schomisch Moravec, John Barnard, David R. Van Wagoner, Mina K. Chung, Jonathan D. Smith
The paper identifies rs17171731 as the causal SNP regulating FAM13B expression linked to atrial fibrillation and shows its effect on cardiomyocyte gene expression and sodium current.
JACC Basic to Translational Science · Jul 27, 2023Peer-reviewedGenomics