Fang Liu

This study shows IL-17A promotes plaque instability in psoriatic atherosclerosis by enhancing macrophage inflammation and disrupting lipid metabolism.

This paper develops zebrafish hand2 Cre and CreERT2 drivers using CRISPR-Cas9 to label mesodermal and ectodermal lineages, revealing lineage contributions to various tissues and vasculature.

This study uses untargeted metabolomics to analyze metabolic changes in the hearts of hypothyroid mice, revealing disruptions in lipid and carbohydrate metabolism.

This study identifies Stat3 as a downstream effector of Fyn kinase in dopaminergic neurodegeneration and microglia activation using a zebrafish model.

This study investigates OR gene expression and regulation in honeybee olfactory sensory neurons using single-cell multi-omics, revealing promoter activation patterns and functional receptor production.

The paper identifies rs17171731 as the causal SNP regulating FAM13B expression linked to atrial fibrillation and shows its effect on cardiomyocyte gene expression and sodium current.

This study shows that dynamic changes in H3K27me3 distribution regulate gene expression programs during cerebellar granule neuron maturation.

This paper describes the generation of two transgenic mouse lines for in vivo epigenome editing using CRISPR-based systems to activate or repress gene expression.

This study identifies a feedforward mechanism in osteoarthritis where IL-1-induced Piezo1 upregulation enhances mechanotransduction and contributes to cartilage damage.