David R. Van Wagoner

This study shows that female mice with cardiac-restricted GRK2 amino-terminal peptide expression develop restrictive cardiomyopathy and metabolic dysregulation under pressure overload, unlike males.

The paper identifies rs17171731 as the causal SNP regulating FAM13B expression linked to atrial fibrillation and shows its effect on cardiomyocyte gene expression and sodium current.

This study uses network-based methods to identify and validate metformin as a potential treatment for atrial fibrillation using human-derived atrial-like cardiomyocytes.

This study identifies AF-associated SNPs in SYNE2 that reduce SYNE21 expression and increase nuclear stiffness, potentially contributing to AF pathogenesis.

The paper assesses if genetic risk for atrial fibrillation explains cardioembolic stroke risk using genome-wide data from the Stroke Genetics Network.

This paper introduces SAPPHO methods to detect pleiotropy in GWAS by modeling shared patterns of genetic associations, finding 16 additional and 124 novel loci in meta-analysis.

This study identifies 47 novel genetic loci associated with PR interval through genome-wide association meta-analysis across multiple populations.