BiochemistrybioRxivPreprint
Discovery and chemical biology of CDK8 inhibitors reveals insights for kinase inhibitor development.
Franck Borel, Y.V. Le Bihan, Béatrice Josselin…·Daniel Fisher
The paper identifies CDK8/19 inhibitors with reduced off-target toxicity and shows that their loss is not cytotoxic but reduces cell proliferation.
DOI 10.1101/2025.11.06.686927