From Structure to Dynamics: Activation Mechanism of the G Protein-Coupled Bile Acid Receptor 1-Gs Complex
Bianca Fiorillo, Federica Moraca, Francesco Saverio Di Leva, Valentina Sepe, Stefano Fiorucci, Vittorio Limongelli, Angela Zampella, Bruno Catalanotti
This study investigates how lithocholic acid modulates GPBAR1 activation and G protein engagement through molecular dynamics simulations and structural analysis.
ACS Omega · Aug 13, 2026Peer-reviewedBioinformatics