Author

Bianca Fiorillo

Federico II University HospitalORCID 0000-0002-3025-5157Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:metabolomics· 1 Approach:mixed model· 1 Organism:mouse· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Angela ZampellaiD· 2 shared Bruno CatalanottiiD· 2 shared Stefano FiorucciiD· 2 shared Valentina SepeiD· 2 shared Alexandra Kalia ParpounasiD· 1 shared Audrey L. WarreniD· 1 shared Bruno CharlieriD· 1 shared Carmen FestaiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersBioinformatics

Angela ZampellaORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

BioinformaticsACS OmegaPeer-reviewedAug 13, 2026

From Structure to Dynamics: Activation Mechanism of the G Protein-Coupled Bile Acid Receptor 1-Gs Complex

Bianca Fiorillo, Federica Moraca, Francesco Saverio Di Leva…·Bruno Catalanotti

This study investigates how lithocholic acid modulates GPBAR1 activation and G protein engagement through molecular dynamics simulations and structural analysis.

DOI 10.1021/acsomega.6c02725

protein structuremixed model

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ImmunologyBiomedicine & PharmacotherapyPeer-reviewedDec 1, 2024

A microbial derived bile acid acts as GPBAR1 agonist and RORγt inverse agonist and reverses inflammation in inflammatory bowel disease

Michele Biagioli, Cristina Di Giorgio, Carmen Massa…·Stefano Fiorucci

This study identifies 3-oxo-DCA as a microbial bile acid that acts as a GPBAR1 agonist and RORγt inverse agonist, reversing inflammation in IBD.

54 citationstop 1%

mousemetabolomics

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NeuroscienceScience AdvancesPeer-reviewedApr 17, 2024

Structural Insights into the Unexpected Agonism of Tetracyclic Antidepressants at Serotonin Receptors 5-HT1eR and 5-HT1FR

Gregory Zilberg, Alexandra Kalia Parpounas, Audrey L. Warren…·Daniel Wacker

The paper investigates the agonist activity of tetracyclic antidepressants at 5-HT1eR and 5-HT1FR, revealing unique binding poses and receptor-specific mechanisms.

7 citations

humanexperimental assay

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