Author

Javier S. Utgés

Institute of Structural and Molecular BiologyORCID 0000-0002-1078-1440Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Approach:contrastive learning· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:dimensionality reduction· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Geoffrey J. BartoniD· 2 shared Brune Le Chatelier· 1 shared Christine Anne OrengoiD· 1 shared David T. JonesiD· 1 shared Diane Lee Zhi Xuan· 1 shared Gopal P. SapkotaiD· 1 shared Lorraine GlennieiD· 1 shared Maxim I. TsenkoviD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersCell Biology

Geoffrey J. BartonORCID

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3 papers

Recent·Most cited

BioinformaticsbioRxivPreprintSep 18, 2026

Interrogating contrastive learning embeddings for structure-based virtual screening: a case study on DrugCLIP

Javier S. Utgés, David T. Jones, Christine Anne Orengo

This paper evaluates DrugCLIP's contrastive learning embeddings for virtual screening, showing strong performance but limitations under realistic conditions.

DOI 10.64898/2026.09.16.752029

structural biologycontrastive learning

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Cell BiologyOpen BiologyPeer-reviewedJan 7, 2026

Mutations within the predicted fragment-binding region of FAM83G/SACK1G abolish its interaction with the Ser/Thr kinase CK1α

Javier S. Utgés, Diane Lee Zhi Xuan, Brune Le Chatelier…·Gopal P. Sapkota

The paper identifies mutations in SACK1G that disrupt its interaction with CK1α, using computational modeling and experimental validation.

DOI 10.1098/rsob.250230

humanproteomics

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BioinformaticsPLoS Computational BiologyPeer-reviewedAug 24, 2021

Ankyrin repeats in context with human population variation

Javier S. Utgés, Maxim I. Tsenkov, Noah J. M. Dietrich…·Geoffrey J. Barton

The paper analyzes human population variants in ankyrin repeats using structural and evolutionary data to identify functionally important sites.

13 citations

humanDNA methylation

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