Author

Anou Moise Somboro

National Center for Disease ControlORCID 0000-0002-1085-7740Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Approach:mixed model· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:protein structure· 1

Frequent Co-Authors

Daniel Gyamfi AmoakoiD· 2 shared Hezekiel Mathambo KumaloiD· 2 shared Ndumiso M. Buthelezi· 2 shared Rene Bernadette KhaniD· 2 shared Elliasu Yakubu SalifuiD· 1 shared Ndumiso Nhlakanipho MhlongoiD· 1 shared Sphamandla E. MtamboiD· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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2 shared papersBioinformatics

Daniel Gyamfi AmoakoORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Molecular Dynamic Investigation of H5N1 Influenza Virus Dual H274Y-I222K Mutation Resistance to Peramivir

Ndumiso M. Buthelezi, Sphamandla E. Mtambo, Daniel Gyamfi Amoako, Anou Moise Somboro, Elliasu Yakubu Salifu, Rene Bernadette Khan, Ndumiso Nhlakanipho Mhlongo, Hezekiel Mathambo Kumalo

This study uses molecular dynamics to analyze how mutations in H5N1 influenza virus neuraminidase affect Peramivir binding, finding that mutations reduce binding stability and drug efficacy.

bioRxiv · Mar 8, 2022 · PreprintBioinformatics

A molecular dynamic investigation of Human Rhinovirus 3C Protease Drug Target: Insights towards the design of potential Inhibitors

Ndumiso M. Buthelezi, Daniel Gyamfi Amoako, Anou Moise Somboro, Rene Bernadette Khan, Hezekiel Mathambo Kumalo

The paper uses molecular dynamics to compare binding affinities of two HRV-3C protease inhibitors, identifying key residues involved in ligand-enzyme interactions.

bioRxiv · Mar 6, 2022 · PreprintBioinformatics