Molecular BiologyProceedings of the National Academy of SciencesPeer-reviewed
Regulation of Ordinal DNA Translocation Cycle in Bacteriophage {varphi}29 through Trans-Subunit Interactions
Rokas Dargis, Joshua Pajak, Pavan Ariyawansa…·Gaurav Arya
This study investigates how the bacteriophage Φ29 DNA packaging motor regulates translocation through trans-subunit interactions, revealing a steric hindrance mechanism involving ATP hydrolysis and DNA gripping.