This study develops HA Tau nanosponges that reduce systemic inflammation and cognitive decline in aged mice by sequestering inflammatory proteins without suppressing immunity.

DOI 10.64898/2026.09.16.752213

mouseexperimental assay

𝕏 PostBluesky

BiophysicsbioRxivPreprintSep 16, 2026

Martini 3 Coarse-Grained Model of DNA for Heterogeneous Molecular Systems

Rokas Dargis, Gaurav Arya

The paper develops a coarse-grained DNA model compatible with the Martini 3 force field, enabling simulations of DNA in diverse molecular systems.

DOI 10.64898/2026.09.14.751576

statistical model

𝕏 PostBluesky

Molecular BiologyProceedings of the National Academy of SciencesPeer-reviewedJul 3, 2025

Regulation of Ordinal DNA Translocation Cycle in Bacteriophage {varphi}29 through Trans-Subunit Interactions

Rokas Dargis, Joshua Pajak, Pavan Ariyawansa…·Gaurav Arya

This study investigates how the bacteriophage Φ29 DNA packaging motor regulates translocation through trans-subunit interactions, revealing a steric hindrance mechanism involving ATP hydrolysis and DNA gripping.

1 citation

bacteria (other)statistical model

𝕏 PostBluesky