Gaurav Arya

This study develops HA Tau nanosponges that reduce systemic inflammation and cognitive decline in aged mice by sequestering inflammatory proteins without suppressing immunity.

The paper develops a coarse-grained DNA model compatible with the Martini 3 force field, enabling simulations of DNA in diverse molecular systems.

This study investigates how the bacteriophage Φ29 DNA packaging motor regulates translocation through trans-subunit interactions, revealing a steric hindrance mechanism involving ATP hydrolysis and DNA gripping.

This study demonstrates the delivery of DNA origami nanorods into live cell nuclei using an antibody against RNA Polymerase II, showing structural integrity and sub-diffusive motion within the nucleus.

The paper presents the first atomic-resolution structure of a viral DNA packaging motor and describes its mechanism through molecular dynamics simulations.