Yang Liu

This study characterizes Asgard archaeal primases, showing they fall into two groups with distinct phylogenetic and functional features, supporting the hypothesis that Asgard archaea are the origin of Eukarya.

The paper identifies archaeal microcompartments in Hodarchaeales, showing they enhance energy production and may have contributed to eukaryogenesis.

This study shows that some Asgard archaea use terminal oxidase and globin for oxygen adaptation, suggesting ancient oxygen tolerance and potential role in eukaryogenesis.

Evolla, a protein-language model, improves functional inference and discovers novel proteins through natural language queries and benchmarking.

This paper reconstructs the evolution of ESCRT systems in archaea, identifying homologs in Asgardarchaeota and other groups, suggesting an early origin of ESCRT components and their connection to the ubiquitin system.

METABOLIC is a software tool for analyzing microbial genomes to predict metabolic functions, interactions, and contributions to biogeochemical cycles, showing better performance than existing tools.

The paper identifies a new Asgard archaea phylum, Hermodarchaeota, capable of degrading alkanes and aromatics via alkyl/benzyl-succinate synthase and benzoyl-CoA pathway in anaerobic sediments.

The paper expands the phylogenetic and metabolic diversity of Asgard archaea and suggests eukaryotes may have originated from an unknown ancestral lineage outside extant archaea.

This study identifies 13 Asgard archaeal subgroups, reveals their widespread distribution in anaerobic environments, and provides evidence of their transcriptionally active mixotrophic lifestyle.